Yesterday around 11:50 a.m., the Kenora OPP was dispatched to a building on fire in the 100 block on Main Street South in the downtown core.
Police arrived on scene shortly after, along with Kenora Fire and Ambulance.
A single deceased male was located inside the structure.
No other victims are known at this point and details will be made available as they come in.
People are being asked to avoid the area to help prevent traffic congestion as crews will be on scene for an undetermined amount of time.
The Fire Marshall also will be attending the scene to investigate the cause of the fire.
Anyone with information regarding this investigation should contact the Kenora OPP immediately toll-free at 1-888-310-1122.
Should you wish to remain anonymous, call Crime Stoppers at 1-800-222-8477 (TIPS).